Research Progress on the Construction and Evaluation of Mouse Models of Pelvic Inflammatory Disease

doi:10. 3969 / j. issn. 1006-6179. 2025. 03. 017

Laboratory Animal Science ›› 2025, Vol. 42 ›› Issue (3): 114-120.DOI: 10. 3969 / j. issn. 1006-6179. 2025. 03. 017

( 1. Clinical College of Traditional Chinese Medicine, Hubei University of Traditional Chinese Medicine, Wuhan 430065, China)

( 2. Jingzhou Hospital of Traditional Chinese Medicine, Hubei University of Traditional Chinese Medicine, Jingzhou 434000, China)

Received:2023-12-27 Online:2025-06-28 Published:2025-07-05

盆腔炎性疾病大鼠模型构建及评价研究进展

( 1. 湖北中医药大学中医学院,武汉 430065) ( 2. 湖北中医药大学附属荆州市中医医院,荆州 434000)

通讯作者: 黄缨( 1969—) ,女,主任医师,博士生导师,研究方向为妇科常见病、疑难病的中医药临床与研究,E-mail:hy3398@ 126. com
作者简介:余婷( 1992—) ,女,主治医师,在读博士,E-mail: 932568678@ qq. com
基金资助:
湖北省自然科学基金项目( 2020CFB718) ;湖北省医学领军人才工程培养项目( [ 2019] 47) ;荆州市中医药研究所自主选题项

目( ZZXT2022Y12)

Abstract

Abstract:

Selecting ideal animal models of pelvic inflammatory diseases is an important basis for the study of pelvic inflammatory diseases, and scientific and systematic model evaluation is the key to further study. In this paper, the pathogenesis, modeling principle, modeling method, modeling evaluation and TCM syndrome evaluation of PID rat model were comprehensively expounded and analyzed, so as to

provide reference for the related research of pelvic inflammatory diseases.

Key words:

pelvic inflammatory disease, rats, animal model, system modelling principle;model evaluation

摘要：

选择理想的盆腔炎性疾病动物模型是进行盆腔炎性疾病相关研究的重要基础,进行科学系统的模型评价是进一步深入研究的关键;本文对盆腔炎性疾病( PID)大鼠模型的发病机制、建模原理、建模方法、建模评价以及中医证候评价等进行综合阐述与分析对比,以期为盆腔炎性疾病相关研究提供参考。

关键词:

盆腔炎性疾病, 大鼠, 动物模型, 系统建模原理, 模型评价

CLC Number:

Q95-3

CHEN Yuhang , YU Ting , HUANG Ying.

Research Progress on the Construction and Evaluation of Mouse Models of Pelvic Inflammatory Disease

[J]. Laboratory Animal Science, 2025, 42(3): 114-120.

陈雨杭, 余婷, 黄缨.

盆腔炎性疾病大鼠模型构建及评价研究进展

[J]. 实验动物科学, 2025, 42(3): 114-120.

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